The raw data of NGS of bystander and Off-target effects in monkey in extended data fig.10c-j.
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To demonstrate that TeABE also functions in a non-human primate model, we performed next-generation sequencing on <i>Macaca mulatta</i> to examine base editing at the CHD3 bystander site and the most likely off-target site, OT1, in both virus-injected and uninjected samples. The results revealed a significant increase in base editing efficiency at both the on-target locus and OT1 following viral injection.
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2025-11-14
