NOTCH1 mutant clones occupy the majority of normal human esophagus by middle age, but are comparatively rare in esophageal cancers, suggesting NOTCH1 mutations may promote clonal expansion but impede

NIAID Data Ecosystem50

Supplementary Table 3 from TP53 Cancerous Mutations Exhibit Selection for Translation Efficiency

癌症基因突变

翻译效率调控

Supplementary Table 3 from TP53 Cancerous Mutations Exhibit Selection for Translation Efficiency

Figshare2009-11-15 更新30

Data from: Mutation screening of 1,237 cancer genes across six model cell lines of basal-like breast cancer

癌症基因突变

乳腺癌研究

Basal-like breast cancer is an aggressive subtype generally characterized as poor prognosis and lacking the expression of the three most important clinical biomarkers, estrogen receptor, progesterone

DataONE2016-01-06 更新50

p53 regulates viral gene expression during infection with human cytomegalovirus. p53 regulates viral gene expression during infection with human cytomegalovirus

病毒基因表达调控

p53功能研究

Human cytomegalovirus (HCMV) is a common cause of morbidity and mortality in immunocompromised and immunosuppressed individuals. During infection, HCMV is known to employ host transcription factors to

NIAID Data Ecosystem40

A systematic p53 mutation library links differential functional impact to cancer mutation pattern and evolutionary conservation. Kotler et al.

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