Comparison of PRSBMI between carriers and noncarriers stratified by BMI category (in adjusted standardized scores).

P values are reported for adjusted means. Model 1 is the adjusted mean of the PRS after including age, sex, and the first 10 principal components in the model. Model 2 is the adjusted mean of the PRS after adding in addition to the covariates in model 1, MET scores, current smoking, and the Townsend Deprivation Index. BMI, body mass index; PRSBMI, polygenic risk score for BMI with mean 0 and SD of 1. (XLSX)