A LOX-simulated enzyme peptide used to promote bone healing in diabetes

To investigate the potential osteogenic mechanism of PMLGH, we performed an mRNA expression profiling microarray. Male Sprague Dawley rats (10 weeks old, 320-350 g weight) were used to test the engineered hydrogels in vivo. For gene expression profiling microarray analysis, tibias were harvested at week 3.为探究PMLGH潜在的成骨机制，我们开展了mRNA表达谱芯片（mRNA expression profiling microarray）实验。本研究选用10周龄、体重320~350g的雄性Sprague Dawley大鼠，用于该工程水凝胶的体内测试。为开展基因表达谱芯片分析，我们于实验第3周收获胫骨样本。