Complete listing of the mutant mouse genes screened and the associated allele information

A subset of genes (29) were screened as 2 different alleles and for 1 gene a total of 3 alleles have been screened. The different alleles were generally tm1a and tm1b to discern if there was any difference after cre-mediated excision of the critical exon and targeting cassette (for details of the EUCOMM/KOMP-CSD tm1a/tm1b allele nomenclature refer to Skarnes et al 9). In some instances, one allele was a point mutation and the other targeting the whole gene. ‘Screened gene’ is the gene name as it appears in Data Record 2, followed by the ‘full allele name’, ‘allele superscript’ and ‘allele MGI ID’ (where a record exists). The ‘unique identifier’ is the internal colony prefix that was used for tracking and is specific to the gene and allele within the institute. In some instances, there are multiple colony prefixes for the same gene and allele – this occurred when additional mice were generated for testing outside of the high-throughput screening project. ‘MGI Gene/Marker ID’ allows tracking of the gene independent of any change in gene name for which a number have changed. The ‘current symbol’ is the most recent gene name and ‘synonym screened’ is where the gene has since been changed at MGI (and also internally) so allows for cross checking to the original data. The full current gene name and feature annotation is listed together with the chromosomal location of the gene and the Ensembl ID.