Binding properties as well as cellular and pore-forming activities of wild-type and LukS-PV mutants1.
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1Ki values, calcium entry slope and ethidium entry at 30 min were obtained for wild-type LukS-PV and all mutants with hPMNs. Ki values with U937-C5aR cells were obtained for wild-type LukS-PV and for the most affected mutants (values given in parenthesis).2Mutations causing a significant decrease in LukS-PV affinity for hPMNs (p
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2015-12-02
