Characterization functional of AcoN-like negative regulator protein from Acetoin cluster in Acinetobacter spp. Strains

Studies of expression of mechanims of defense of the Acinetobacter sp.5-2Ac.02 from airborne hospital environment under stress conditions, such as SOS response (ROS response, heavy metals resistant mechanisms, peptides), as well as Quorum network (acetoin cluster and aromatics biodegradation cluster). Characterization functional of AcoN-like as negative regulator protein from acetoin cluster in Acinetobacter spp. Strains We worked with Acinetobacter sp.5-2Ac.02 from airborne (species close to Acinetobacter towneri) which genome of the strain has been sequenced by Barbosa et al. (21) (GenBank accession number. MKQS00000000; Bioproject PRJNA345289). Moreover, we used the Acinetobacter baumannii ATCC17978 (GenBank accession number CP018664.1), as well as two isogenic mutants, A. baumannii 17978ATCCΔacoN which was obtained in this study and A. baumannii 17978ATCCΔabaI from Castañeda-Tamez et al.