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Leishmania major N-myristoyltransferase in complex with a pyrrolidine inhibitor.

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4cyp
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Leishmania major N-myristoyltransferase in complex with a pyrrolidine inhibitor. Descriptor: (3R)-4-(4-chlorophenyl)-1-[(3S,4R)-3-(4-chlorophenyl)-4-(hydroxymethyl)pyrrolidin-1-yl]-3-hydroxybutan-1-one, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, ... Authors: Hutton, J.A, Goncalves, V, Brannigan, J.A, Paape, D, Waugh, T, Roberts, S.M, Bell, A.S, Wilkinson, A.J, Smith, D.F, Leatherbarrow, R.J, Tate, E.W. Deposit date: 2014-04-14 Release date: 2014-10-22 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structure-Based Design of Potent and Selective Leishmania N- Myristoyltransferase Inhibitors. J.Med.Chem., 57, 2014
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2014-04-14
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