Eukaryotic Ribosomal Internal Transcribed Spacer 1 Database

The Eukaryotic Ribosomal Internal Transcribed Spacer 1 Database (ITSoneDB) is a collection of eukaryotic ribosomal RNA Internal Transcribed Spacer 1 (ITS1) sequences. It is intended to provide a curated reference database aimed at ITS1-based metagenomic surveys. Each ITS1 is mapped on the NCBI reference taxonomy with its start and end positions precisely annotated. ITSoneDB has been developed in agreement to the FAIR guidelines by enabling the users to query and download its content through a simple web-interface and access relevant metadata by cross-linking to European Nucleotide Archive.真核生物核糖体内部转录间隔区1数据库（ITSoneDB）收录了一系列真核生物核糖体RNA内部转录间隔区1（ITS1）序列。该数据库旨在为基于ITS1的宏基因组调查提供经人工审校的参考数据库。每条ITS1序列均匹配至NCBI参考分类学体系，其起始与终止位置均经过精准注释。ITSoneDB遵循FAIR指南开发，支持用户通过简洁的网页界面查询并下载数据库内容，还可通过与欧洲核苷酸档案库（European Nucleotide Archive）交叉链接获取相关元数据。

搜集汇总

背景与挑战

背景概述

ITSoneDB是一个真核生物核糖体RNA内部转录间隔区1（ITS1）序列的参考数据库，基于欧洲核苷酸档案（ENA）构建，旨在支持基于ITS1的宏基因组调查。该数据库通过ENA注释和HMM图谱映射精确标注ITS1边界，并遵循FAIR原则提供查询和下载功能。