Managed clinical protocol: impact of implementation on sepsis treatment quality indicators

ABSTRACT Objectives: to assess the impact of the implementation of a managed sepsis protocol on quality indicators of treatment for septic patients in an emergency department of a university hospital. Methods: an observational epidemiological study involving septic patients. The study was divided into two phases, pre-intervention and intervention, resulting from the implementation of the managed sepsis protocol. The study variables included sepsis treatment quality indicators. The results were statistically analyzed using the program Epi InfoTM. Results: the study sample included 631 patients, 95 from pre-intervention phase and 536 from intervention phases. Implementing the protocol increased patients’ chances of receiving the recommended treatment by 14 times. Implementing the protocol reduced the hospitalization period by 6 days (p &lt;0.001) and decreased mortality (p &lt;0.001). Conclusions: this study showed that implementing the managed protocol had an impact on the improvement of sepsis treatment quality indicators.摘要 研究目的：评估实施脓毒症（sepsis）规范化管理方案对某大学医院急诊科脓毒症患者治疗质量指标的影响。 研究方法：本研究为观察性流行病学研究，纳入脓毒症患者。研究分为干预前、干预两个阶段，干预阶段对应脓毒症规范化管理方案的落地实施；研究变量涵盖脓毒症治疗质量指标，采用Epi InfoTM软件完成统计学分析。 研究结果：本研究共纳入631例患者，其中干预前阶段95例，干预阶段536例。实施该方案可使患者接受推荐治疗的几率提升14倍；可将住院时长缩短6天（p<0.001），同时降低患者死亡率（p<0.001）。 研究结论：本研究证实，实施脓毒症规范化管理方案可有效改善脓毒症治疗质量指标。