Nonclassical beta catenin signaling regulate skeletal cell fate determination
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https://www.ncbi.nlm.nih.gov/sra/SRP383566
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To rigorously examine the role of b-catenin dependent transcription, we created mice deficient for the transcriptional output of beta-catenin in skeletal mesenchyme (bcat-dTF-Dermo1-cKO) and compare the transcriptional profiles to that of the beta-catenin conditional KO mice in skeletal mesenchyme (bcat-Dermo1-cKO). Overall design: Total RNAs were isolated from calvarial mesenchyme at E15.5 and followed by comparative gene expression profiling analysis of RNA-seq data for control, bcat-dTF-Dermo1-cKO, and bcat-Dermo1-cKO.
创建时间:
2023-01-05



