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Crystal structure of the second bromodomain (BD2) of human BRD4 bound to SG3-179

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of the second bromodomain (BD2) of human BRD4 bound to SG3-179 Descriptor: 1,2-ETHANEDIOL, 4-[[4-[[3-(~{tert}-butylsulfonylamino)-4-chloranyl-phenyl]amino]-5-methyl-pyrimidin-2-yl]amino]-2-fluoranyl-~{N}-(1-methylpiperidin-4-yl)benzamide, Bromodomain-containing protein 4 Authors: Karim, M.R, Zhu, J.Y, Schonbrunn, E. Deposit date: 2020-11-06 Release date: 2021-10-20 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors. J.Med.Chem., 64, 2021
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2020-11-06
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