EGFR(T790M/V948R) in complex with compound 2 (LN5993)
收藏Protein Data Bank Japan2024-03-20 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8fv4
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EGFR(T790M/V948R) in complex with compound 2 (LN5993) Descriptor: Epidermal growth factor receptor, MAGNESIUM ION, N-{(3P)-3-[(4P)-4-(2-acetamidopyridin-4-yl)-2-(methylsulfanyl)-1H-imidazol-5-yl]phenyl}-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepine-9-carboxamide, ... Authors: Ogboo, B.C, Beyett, T.S, Eck, M.J, Heppner, D.E. Deposit date: 2023-01-18 Release date: 2024-01-17 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors. Commun Chem, 7, 2024
创建时间：
2023-01-18
