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Role of FGF-2 induced non-coding RNA in cancer [II]

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https://www.ncbi.nlm.nih.gov/sra/SRP349305
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资源简介:
We show that IER3 and IER3-AS1 protein coding and non-coding genes mediates oncogenic properties in cancer cell lines when they are induced by FGF-2 which is fibroblast growth factor. Comprehensive analysis of mechanisms behind the regulation of these genes by FGF-2 induction is shown in this study. Overall design: Characterization of FGF-2 regulated transcriptome in immortalized human embryonic kidney cells HEK293 and cancer cell lines such as HeLa and BT-549 in order to identify common and uniquely enriched FGF-2 regulated differentially expressed genes and biological pathways.
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2022-09-16
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