The NAD + Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC, iPSC derived Neural Stem Cells and cortical Organoid of Alpers’ Disease

To investigate the transcriptomic profile and molecular machnisiums using RNA sequecning analysis for the iPSC derived neural cells and brain organoids from the patient of Alpers’ Disease We then performed gene expression profiling analysis using data obtained from RNA-seq of the iPSC derived neural cells and brain organoids from the patient of Alpers’ Disease and healthy controls Comparative gene expression profiling analysis of RNA-seq data for neural cells and brain organoids from the patient of Alpers’ Disease and healthy controls **RAW data not provided due to patient privacy laws**