CIL:39587, Saccharomyces cerevisiae. In Cell Image Library

A time lapse experiment of Saccharomyces cerevisiae expressing GFP-tagged SWI5. SWI5 is a transcription factor that recruits the Mediator and Swi/Snf complexes; activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; is required for expression of the HO gene controlling mating type switching; and whose localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase. These phase,gfp z-series images are part of an image group that ranges from CIL:39586-39590. Note that there are additional groups showing time series of other cell cycle regulation proteins by the same authors in the Library.

本数据集为表达绿色荧光蛋白（Green Fluorescent Protein，GFP）标记SWI5的酿酒酵母（Saccharomyces cerevisiae）延时成像实验。SWI5是一类转录因子，可招募中介体（Mediator）与Swi/Snf复合物；能够激活在M/G1期边界及G1期表达的基因的转录；是调控交配型转换的HO基因表达所必需的；其向细胞核的定位过程发生于G1期，且似乎受Cdc28p激酶的磷酸化调控。此类相差成像与GFP标记的Z轴序列成像图像属于编号范围为CIL:39586至39590的图像组的一部分。需注意，该图库中另有同作者发布的其他细胞周期调控蛋白的延时成像图像组。