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Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation S87L

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Protein Data Bank Japan2024-05-01 更新2026-03-21 收录
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Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation S87L Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MORC family CW-type zinc finger protein 2, ... Authors: Douse, C.H, Liu, Y, Modis, Y. Deposit date: 2017-07-10 Release date: 2018-02-14 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms. Nat Commun, 9, 2018
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2017-07-10
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