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Structure of murine iNOS oxygenase domain with inhibitor AR-C102222

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Structure of murine iNOS oxygenase domain with inhibitor AR-C102222 Descriptor: 1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE, 7,8-DIHYDROBIOPTERIN, Nitric oxide synthase, ... Authors: Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stuehr, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D. Deposit date: 2008-08-18 Release date: 2008-10-07 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat.Chem.Biol., 4, 2008
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2008-08-18
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