Efficient Construction of Proline-Containing β‑Turn Mimetic Cyclic Tetrapeptides via CuAAC Macrocyclization
收藏NIAID Data Ecosystem2026-03-07 收录
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资源简介：
A range of macrocyclic β-turn mimetic tetrapeptides was prepared by efficient copper-tris(triazole) ligand complex catalyzed azide–alkyne “click” macrocyclizations in good to high yields. Preliminary conformational studies using X-ray crystallography and NMR spectroscopy demonstrated the presence of intramolecular H-bonds characteristic of β-turns in these cyclic tetrapeptides.
创建时间：
2016-02-19
