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Crystal structure of CD38 with a novel CD38-targeting antibody SAR650984

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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Crystal structure of CD38 with a novel CD38-targeting antibody SAR650984 Descriptor: ADP-RIBOSYL CYCLASE 1, HEAVY CHAIN OF SAR650984-FAB FRAGMENT, LIGHT CHAIN OF SAR650984-FAB FRAGMENT Authors: Deckert, J, Wetzel, M.C, Park, P.U, Bartle, L.M, Skaletskaya, A, Goldmacher, V, Vallee, F, ZhouLiu, Q, Ferrari, P, Pouzieux, S, Lahoute, C, Dumontet, C, Plesa, A, Chiron, M, Lejeune, P, Chittenden, T, Blanc, V. Deposit date: 2014-01-15 Release date: 2014-07-16 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.53 Å) Cite: SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies. Clin. Cancer Res., 20, 2014
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2014-01-15
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