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Chiral Phosphoric Acid Catalyzed Intramolecular Dearomative Michael Addition of Indoles to Enones

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Figshare2017-02-01 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Chiral_Phosphoric_Acid_Catalyzed_Intramolecular_Dearomative_Michael_Addition_of_Indoles_to_Enones/4602388
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An enantioselective intramolecular dearomative Michael addition of indolyl enones is presented. In the presence of catalytic amount of chiral phosphoric acid, various enantioenriched spiro-indolenines bearing a quaternary stereogenic center were obtained with good yields and enantioselectivity (up to 97% ee) under mild reaction conditions.
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2017-02-01
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