Distinct changes in microbiota-mediated intestinal metabolites and immune responses induced by different antibiotics. undefined

The cocktails of antibiotics are utilized to study the functions of microbiota. However, the effect of each antibiotic on the host in terms of immunity and metabolism cannot be determined. Therefore, we supplied mice with drinking water containing ampicillin (AMP), vancomycin (VAN), neomycin (NEO), or metronidazole (MET) to observe the effect of each antibiotic on helper T cell and inflammation-related gene expression and metabolism, including amino acid metabolism and changes in gut microbiota.