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DNA polymerase beta with a gapped DNA substrate and dTMP(CF2)P(CF2)P

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Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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DNA polymerase beta with a gapped DNA substrate and dTMP(CF2)P(CF2)P Descriptor: 5'-O-[(R)-{[(R)-[difluoro(phosphono)methyl](hydroxy)phosphoryl](difluoro)methyl}(hydroxy)phosphoryl]thymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Zibinsky, M, Surya Prakash, G.K, Upton, T.G, Kashemirov, B.A, McKenna, C.E, Oertell, K, Goodman, M.F, Batra, V.K, Pedersen, L.C, Beard, W.A, Wilson, S.H. Deposit date: 2010-01-27 Release date: 2011-01-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. Proc.Natl.Acad.Sci.USA, 107, 2010
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2010-01-27
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