Gene expression analysis of cardiomyocytes treated with a clinically relevant concentration of DEHP (50 ug/mL)
收藏Alliance of Genome Resources2026-08-01 收录
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We used microarrays to expression profile cardiomyocytes from neonatal Sprague-Dawley rats treated with 50 ug/mL DEHP and control (0.1% DMSO) to identify changes in gene expression related to connexin-43 expression, calcium handling, arrhythmogenesis and mechanical motion.
本研究采用微阵列芯片(microarray)技术,对经50 μg/mL DEHP处理及0.1%二甲基亚砜(DMSO)对照处理的新生斯普拉格-道利大鼠心肌细胞进行基因表达谱分析,以鉴定与连接蛋白43(connexin-43)表达、钙离子调控、致心律失常发生及机械运动相关的基因表达变化



