Interleukin-17 governs hypoxic adaptation of injured epithelium [bulk RNA-seq]

RORgt deficency impaired wound re-epithelialization. We adopted low-input RNA-seq of purified wound epithelium to explore the underlying epithelial cell functional difference between wild type and RORgt deficient mice during wound healing.RORgt缺陷会损害伤口再上皮化过程。本研究采用纯化伤口上皮细胞的低起始量RNA测序技术，探究野生型与RORgt缺陷小鼠在伤口愈合过程中上皮细胞的潜在功能差异。