Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 18
收藏数据链接：
官方服务：
资源简介：
Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 18 Descriptor: 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, ... Authors: Whittington, D.A. Deposit date: 2025-12-08 Release date: 2026-05-27 Last modified: 2026-06-24 Method: X-RAY DIFFRACTION (1.71 Å) Cite: The Discovery of TNG456: A Highly Potent, Selective, Brain-Penetrant MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP -Deleted Cancers. J.Med.Chem., 69, 2026
创建时间：
2025-12-08
