Protective effect of ocular HPC on retinal damage induced by glutamate.

Total retinal and retinal layer thicknesses (in µm) and retinal ganglion cell number in vehicle- or glutamate-injected eyes without or with ocular HPC. Glutamate induced a decrease in total retinal, INL, and IPL thickness and Brn3a(+) cell number, which was significantly prevented by ocular HPC. Data are mean ± SEM (n = 5 eyes per group).*P**P aP bPPS, photoreceptor outer and inner segment; OPL, outer plexiform layer; ONL, outer nuclear layer; IPL, inner plexiform layer; INL, inner nuclear layer; GCL, ganglion cell layer.