Genome wide analysis of thoracic spinal cord at 5 days after T9 hemisection injury.

The goal of this study is to elucidate the influence of hemisection injury at thoracic spinal cord (T9) and epidural electrical spinal stimulation (L2-S1) on transcriptome of injured thoracic spinal cord. mRNA profiles of spinal cord at 5 days-post injury with or without epidural electrical spinal stimulation (L2-S1) and before injury were generated. Our study represents the detailed analysis of transcriptomes of injured spinal cord with biologic replicates, generated by RNA-seq technology. The effect of epidural electrical spinal stimulation (L2-S1) after spinal cord injury on the transcriptom of injured spinal cord (T9) was investigated.