EC-8P

EC-8P investigates the impact of Lactobacillus paracasei treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample EC-8P:<br>E: Denotes the strain ST-37 of Clostridioides difficile.<br>C: Represents timepoint 2, indicating sampling after C. difficile infection.<br>8: Refers to the specific mouse number under investigation.<br>P: Indicates the treatment administered, which in this case is Lactobacillus paracaseEC-8P数据集旨在探究副干酪乳杆菌（Lactobacillus paracasei）干预对艰难梭菌（Clostridioides difficile）感染小鼠肠道菌群的影响。本研究对感染后小鼠的粪便样本采用英维创（Invitrogen）相关试剂盒进行前处理，并通过Ion Torrent下一代测序（NGS）系统完成测序。借助Ion Reporter SW（16S）软件开展分析后，研究人员观察到感染后第1、3、6天的微生物类群动态变化，为阐明益生菌在艰难梭菌感染期间调控肠道菌群的潜在价值提供了依据。样本EC-8P的命名规则如下：<br>E：代表艰难梭菌（Clostridioides difficile）菌株ST-37；<br>C：表示时间节点2，即艰难梭菌感染后采样的时间点；<br>8：指代本次研究中的特定受试小鼠编号；<br>P：表示本次施加的干预处理方式，本案例中为副干酪乳杆菌干预。