Research data supporting: "Dysregulation of ADAM10 shedding activity in naked mole-rat fibroblasts is due to deficient phosphatidylserine externalisation"

There is a Prism file providing the raw data, including statistical analyses, aligning to each of the figures: $$ \ $$ Figure 1.pzfx - CD44 cleavage assay in mouse and naked mole-rat primary skin fibroblasts $$ \ $$ Figure 2.pzfx - Measurement of cellular ADAM10 levels and betacellulin cleavage in mouse and naked mole-rat primary skin fibroblasts $$ \ $$ Figure 3.pzfx - CD44 and betacellulin cleavage assays in mouse and naked mole-rat transformed skin fibroblasts $$ \ $$ Figure 4.pzfx - Plasma membrane phosphatidlylserine quantification in mouse and naked mole-rat primary skin fibroblasts $$ \ $$ Figure 5.pzfx - Analysis of plasma membrane phosphatidlylserine levels and betacellulin cleavage in mouse and naked mole-rat primary skin fibroblasts overexpressing either GFP or the scramblase ANO6 $$ \ $$ Figure 6.pzfx - Analysis of cellular wound closure in naked mole-rat primary skin fibroblasts overexpressing either GFP or the scramblase ANO6, and the impact of inhibiting ADAM10 $$ \ $$ Supplementary Figure 1.pzfx - Concentration response relationship for ionomycin induced CD44 cleavage in mouse and naked mole-rat primary skin fibroblasts $$ \ $$ Supplementary Figure 2.pzfx - Concentration response relationship for ionomycin induced CD44 cleavage in transformed mouse and naked mole-rat skin fibroblasts $$ \ $$ Supplementary Figure 3.pzfx - Levels of cellular ADAM10 levels in mouse and naked mole-rat transformed skin fibroblasts $$ \ $$ Supplementary Figure 4.pzfx - Analysis of plasma membrane phosphatidlylserine levels and betacellulin cleavage in mouse primary skin fibroblasts overexpressing either GFP or the scramblase ANO6, carried out at 32°C $$ \ $$ Supplementary Figure 5.pzfx - Analysis of ANO6 protein levels in mouse and naked mole-rat transformed fibroblasts $$ \ $$ Supplementary Figure 6.pzfx - Analysis of cellular wound closure in mouse primary skin fibroblasts overexpressing either GFP or the scramblase ANO6, and showing the impact of ADAM10 inhibition, carried out at 32°C and 37°C