Expression of Interferon-regulated genes by EBV and CD40L/IL4 blasts.
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*Numbers in parentheses indicate the number of genes within the gene-set analyzed.Comparisons were restricted to the 16420 genes present on both the HuExon 1.0 ST and the U133 plus2 Affymetrix array platforms. The size of each comparator gene-set was selected to ensure as far as was practical that similar-sized sets were being analyzed. For example, genes up-regulated by EBV were ranked in order of FC, and the top 370 were selected for comparison with the 370 ISGs. Complete gene-lists are available in Data-File S2. (A) Of the 389 ISGs described by Schoggins et al[31] through meta-analysis of published arrays, 370 were present in the 16420 annotated genes common to both array platforms. (B) Of the 124 unique genes identified experimentally by Schoggins et al[31] as being up-regulated by IRF-1, 113 were present in the 16420 annotated genes common to both array platforms.
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2015-12-02



