perinatal factors in child brain-mind development (periCBD)

Adverse perinatal factors can interfere with the normal development of the brain, potentially resulting in long-term effects on the comprehensive development of children. Presently, the understanding of cognitive and neurodevelopmental processes under conditions of adverse perinatal factors is substantially limited. There is a critical need for an open resource that integrates various perinatal factors with the development of the brain and mental health to facilitate a deeper understanding of these developmental trajectories.In this Data Descriptor, we introduce a multicentre database containing information on perinatal factors that can potentially influence children's brain-mind development, namely, periCBD, that combines neuroimaging and behavioural phenotypes with perinatal factors at county/region/central district hospitals. PeriCBD was designed to establish a platform for the investigation of individual differences in brain-mind development associated with perinatal factors among children aged 3–10 years. Ultimately, our goal is to help understand how different adverse perinatal factors specifically impact cognitive development and neurodevelopment. Herein, we provide a systematic overview of the data acquisition/cleaning/quality control/sharing, processes of periCBD and present preliminary brain-mind associations.

围产期不良因素可干扰大脑正常发育，进而可能对儿童的全面发育造成长期不良影响。当前学界对围产期不良因素作用下的认知与神经发育进程的认知仍存在显著局限。目前亟需构建一项开放型研究资源，整合各类围产期因素与大脑及心理健康发育的关联数据，以推动学界对这些发育轨迹的深入解析。在《数据描述》（Data Descriptor）栏目文章中，我们介绍了一款可潜在影响儿童脑-心智发育的围产期因素相关多中心数据库——围产期脑-心智发育关联数据库（periCBD），该库整合了县/区域/中心城区医院采集的神经影像（neuroimaging）、行为表型（behavioural phenotypes）与围产期因素数据。围产期脑-心智发育关联数据库的设计初衷是搭建研究平台，用于探究3~10岁儿童中与围产期因素相关的脑-心智发育个体差异。本研究的最终目标是助力学界厘清不同围产期不良因素对认知发育与神经发育的特异性影响。本文系统梳理了periCBD的数据采集、清洗、质量控制与共享流程，并展示了初步的脑-心智关联分析结果。

搜集汇总

背景与挑战

背景概述

该数据集是一个多中心数据库，整合了可能影响儿童大脑和心理发展的围产期因素，包含3-10岁儿童的神经影像和行为表型数据。数据集旨在研究围产期因素与儿童大脑心理发展个体差异的关系，数据量为39.76GB，需申请访问权限。