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Effects of PFKFB4 deletion on transcriptional reprogramming in breast cancer cells

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE217132
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To explore the mechanisms by which PFKFB4 promotes breast cancer metastasis, we CRISPR-Cas knock-out PFKFB4 in two breast cancer lines for RNA-seq to identify downstream target genes that are regulated by PFKFB4 Single-end mRNA sequencing was performed from wild-type (WT) or PFKFB4-knock-out (PFKFB4-KO) mouse EMT6 and human MDA-MB-231 breast cancer cells
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2023-01-11
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