Grass carp gut with GCRV-II infection

In vertebrates, survival during infection depends on the coordination between the host immune system and the gut microbiota. However, the crosstalk between gut microbiota and immune responses under pathogenic pressure remains poorly characterized in teleost fish. In this study, we performed transcriptomic and 16S rRNA sequencing to investigate the dynamic change of intestinal immunity and microbial communities following infection with grass carp reovirus genotype II (GCRV-II).