Christopher Woodcock, Tatiana Nikitina (2010) CIL:126, Gallus gallus gallus, erythrocyte. CIL. Dataset

Telomeres isolated from chicken erythrocyte nuclei following restriction endonuclease treatment, and imaged by transmission EM after uranyl acetate negative staining. Specimen was also labeled with immunogold using an anti-TRF1 primary antibody. Telomere chromatin adopts a characteristic looped conformation which likely aids in protection from the rapid degradation that occurs with free DNA ends.

经限制性核酸内切酶处理从鸡红细胞核中分离出的端粒，经铀酰醋酸盐负染色后，通过透射电子显微镜进行成像。样品还通过抗TRF1一抗进行免疫金标记。端粒染色质呈现出特有的环状构象，这种构象可能有助于抵抗游离DNA末端发生的快速降解过程。