Clearance of endogenous uric acid in oxonate-treated rats.
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Clearance of endogenous uric acid was measured in oxonate-treated rats. Urine, bile and blood were collected up to 60 min and clearances were calculated by dividing the amount excreted into each part by plasma AUC. Estimated intestinal clearance was obtained as described in Materials and methods using mean value of 5 individual measurements; 118±2.52 cm for length for jejunum and 15.7±0.33 cm for colon, respectively. Values indicate mean ± S.E.M. (n = 5).
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2015-12-02



