Transcriptome analysis of overexpressed SNCA in differentiated SH-SY5Y neuroblastoma cells
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https://www.ncbi.nlm.nih.gov/sra/SRP259115
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资源简介：
The goal of this study is to compare NGS-derived transcriptome profiling (RNA-seq) of alpha-synuclein expressing Sh-SY5Y cells vs. lacZ control protein and find characteristic changes that may be related to alpha-synucleinopathies. Our results showed the enrichments of p53 pathways, DNA damage responses, and cellular senescence. Further studies validated genes involved in such pathways. Overall design: To obtain transcriptome profiling after ectopic SNCA expression.
创建时间：
2022-03-11
