SC3 clusters and gene marker testing results.

The numbers of gene markers in SC3 clusters (n = 40) were determined by defining the area under receiver operating characteristic (AUROC) value (> 0.80) and adjusted P-value (< 0.05). The numbers of gene markers can be explored based on different AUROC values (0.8 to 1), in which gene markers (defined by AUROC > 0.95, highlighted in red color) are presented in Fig 5. Abbreviations: padj, a multiple comparison adjusted P-value calculated for each gene marker using the Wilcoxon signed rank test; de_padj, a multiple comparison adjusted P-value for differentially expressed (de) genes using the non-parametric Kruskal-Wallis test, representing the likelihood of stochastically expressing a gene in one cluster over other cluster(s).
(XLSX)