Transcriptional changes upon Jagn1 loss in LPS-stimulated plasmablasts.
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https://www.ncbi.nlm.nih.gov/sra/SRP235126
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资源简介：
We report that Jagn1-deficiency is associated with alterations in the ER of antibody-producing cells and decreased immunoglobulin levels. By doing QuantSeq of FACS-sorted CD22-CD138+ plasmablasts, we found several differentially expressed genes in Jagn1DB knock-out mice. Overall design: Examination of consequences of B-cell specific knock-out of Jagn1 in LPS-stimulated splenic B cells (from 4 mice per genotype), which were FACS-sorted for CD22-CD138+ plasmablasts after 4 days of LPS stimulation.
创建时间：
2020-08-13
