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Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program

ChEBI2011-02-14 更新2026-07-21 收录

B细胞发育

发育转录调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-26408 数据链接链接失效反馈

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Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program

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创建时间：

2011-02-14

B细胞发育

信号转导分析

We examined the global gene expression profile of PLCγ1/PLCγ2 double-deficient CLPsand B cell progenitors by RNA-seq analysis. Overall design: CLPs (Lin-IL-7R+) and B cell progenitors (B220+IgM-IL-7R+

NIAID Data Ecosystem100

Additional file 7 of Tissue-specific RNA Polymerase II promoter-proximal pause release and burst kinetics in a Drosophila embryonic patterning network

发育转录调控

表观遗传学技术

Additional file 7 Tables S8 and S9. List of primer sequences, and PRO-seq, ChIP-seq, ATAC-seq and CUT&Tag library mapping information.

Figshare2024-08-18 更新60

A developmental program truncates long transcripts to temporally regulate cell signaling

发育转录调控

细胞信号机制

Rapid mitotic divisions and a fixed transcription rate limit the maximal length of transcripts in early embryos. Previous studies suggested that transcription of long genes is initiated, but then abor

NIAID Data Ecosystem20

The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement. The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement

B细胞发育

剪接体功能

The spliceosome is a large ribonucleoprotein complex responsible for pre-mRNA splicing and genome stability maintenance. Disruption of the spliceosome activity may lead to developmental disorders and

NIAID Data Ecosystem60

BCR and TLR-induced IRF1 promotes T cell independent B cell responses by supporting Notch2 dependent Marginal Zone B cell development

B细胞发育

T细胞非依赖性抗体应答

The prototypic interferon (IFN)-inducible transcription factor, IRF1, not only controls expression of IFN genes but also regulates T cell and macrophage fate specification and function. We show that I

NIAID Data Ecosystem40

Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program

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