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Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41 and a tethered phosphate moiety.

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Protein Data Bank Japan2023-12-06 更新2026-03-21 收录
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Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41 and a tethered phosphate moiety. Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41) Authors: Irimia, A, Wilson, I.A. Deposit date: 2013-11-01 Release date: 2014-12-03 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies. Nat.Struct.Mol.Biol., 21, 2014
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2013-11-01
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