It is well-established that mitophagy leads to Diabetic Nephropathy (DN) and renal failure. Mitophagy mediated by a Hypoxia-inducible factor-1α (HIF-1α) plays a beneficial role in many diseases. Never

NIAID Data Ecosystem20

Data Sheet 7_Investigating the metabolic reprogramming mechanisms in diabetic nephropathy: a comprehensive analysis using bioinformatics and machine learning.csv

肾病分子机制

生物标志物发现

BackgroundDiabetic nephropathy (DN) is a common complication of diabetes, characterized by damage to renal tubules and glomeruli, leading to progressive renal dysfunction. The aim of our study is to e

NIAID Data Ecosystem00

Table_5_Molecular mechanisms governing the progression of nephritis in lupus prone mice and human lupus patients.xlsx

狼疮肾炎进展机制

基因表达谱分析

IntroductionPathologic inflammation is a major driver of kidney damage in lupus nephritis (LN), but the immune mechanisms of disease progression and risk factors for end organ damage are poorly unders

NIAID Data Ecosystem30

Hepatic tissue expression profiles of Acsm3 knockout and control mice.

代谢机制研究

基因表达谱分析

Acyl-CoA synthetase medium-chain family member 3 (ACSM3) is one member of ACSM family and localized on the outer membrane of mitochondria, which catalyzes the activation of medium-chain (C4-C14) lengt

Alliance of Genome Resources00

Gene expression analysis of diabetic kidney cortices obtained from ICAM-1 deficient mice and wild type mice.

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