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Structure of human ceramide synthase 6 (CerS6) bound to C16:0 (nanobody Nb02)

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Protein Data Bank Japan2025-03-26 更新2026-04-25 收录
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Structure of human ceramide synthase 6 (CerS6) bound to C16:0 (nanobody Nb02) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Ceramide synthase 6, ... Authors: Pascoa, T.C, Pike, A.C.W, Chi, G, Stefanic, S, Quigley, A, Chalk, R, Mukhopadhyay, S.M.M, Venkaya, S, Dix, C, Moreira, T, Tessitore, A, Cole, V, Chu, A, Elkins, J.M, Pautsch, A, Schnapp, G, Carpenter, E.P, Sauer, D.B. Deposit date: 2024-03-15 Release date: 2024-11-13 Last modified: 2025-03-26 Method: ELECTRON MICROSCOPY (3.02 Å) Cite: Structural basis of the mechanism and inhibition of a human ceramide synthase. Nat.Struct.Mol.Biol., 32, 2025
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2024-03-15
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