Concentration-dependent induction of RR in HEp-2 cells using different CTPS1 and IMPDH2 inhibitors for 24 h.
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1Ribavirin induced RR in nearly all cells regardless of the tested concentration (0.2 µM–2 mM). There is no statistical significance (ns) between concentrations after Bonferroni's adjustment except with untreated control (0 µM; p>0.005);2DON induced RR in most cells at concentrations higher than 0.5 mM (p3Acivicin started to induce RR at 15.6 µM and concentrations higher than 31.3 µM, nearly all cells had RR (p4ns between Ribavirin, DON, or Acivicin;5Ribavirin vs DON, p6Ribavirin vs DON, p7Ribavirin vs DON, p
创建时间：
2015-12-02
