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CryoEM structure of human GARP-lTGFbeta1 in complex with a Fab fragment derived from an activating antibody.

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Protein Data Bank Japan2025-10-08 更新2026-04-25 收录
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CryoEM structure of human GARP-lTGFbeta1 in complex with a Fab fragment derived from an activating antibody. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Transforming growth factor beta activator LRRC32, ... Authors: Felix, J, Lambert, F, Marien, L, van der Woning, B, Savvides, S.N, Lucas, S. Deposit date: 2023-12-12 Release date: 2025-03-26 Last modified: 2025-10-08 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Antibody-mediated TGF-beta 1 activation for the treatment of diseases caused by deleterious T cell activity. Cell Rep, 44, 2025
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2023-12-12
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