DiffModeler: Large Macromolecular Structure Modeling in Low-Resolution Cryo-EM Maps Using Diffusion Model

Here, we store the modeled structures generated by DiffModeler for its 4 benchmark datasets: CryoREAD dataset(0-5A resolution, protein-DNA/RNA complex), ModelAngelo dataset(0-5A resolution, most protein complexes, a few protein-RNA complex), intermediate resolution dataset (5-10A resolution, protein complex), low resolution dataset (10-20A resolution, protein complex). For all protein-DNA/RNA complex, the map will be modeled by CryoREAD+DiffModeler. For each dataset, we keep the modeled structures by DiffModeler, named as [EMD-ID]_DiffModeler.cif; and their corressponding native structures from RCSB are saved as [EMD-ID]_[PDB_ID]_native.cif. For CryoREAD dataset, it includes 61 targets. For ModelAngelo dataset, it includes 28 targets. For intermediate resolution dataset , it includes 19 targets. For low resolution dataset, it incldues 6 targets. If you used DiffModeler, please cite: "Wang, Xiao, Han Zhu, Genki Terashi, Manav Taluja, and Daisuke Kihara. "DiffModeler: Large Macromolecular Structure Modeling in Low-Resolution Cryo-EM Maps Using Diffusion Model." bioRxiv (2024): 2024-01.". If you used CryoREAD, please cite: "Xiao Wang, Genki Terashi & Daisuke Kihara. De novo structure modeling for nucleic acids in cryo-EM maps using deep learning. Nature Methods, 2023."