Cryo-EM structure of Vibrio cholerae RNA polymerase Transcription Activation Complex with ToxR and TcpP transcription factors and a toxT promoter DNA fragment

Cryo-EM structure of Vibrio cholerae RNA polymerase Transcription Activation Complex with ToxR and TcpP transcription factors and a toxT promoter DNA fragment Descriptor: Cholera toxin transcriptional activator, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Alcaide-Jimenez, A, Baudin, F, Canals, A, Machon, C, Murciano, B, Fabrega-Ferrer, M, Bantysh, O, Perez-Luque, R, Krukonis, E.S, Muller, C.W, Coll, M. Deposit date: 2024-08-06 Release date: 2025-12-17 Last modified: 2026-01-28 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures of Vibrio cholerae transcription complexes reveal how ToxR and TcpP recruit the RNA polymerase and activate virulence genes. Sci Adv, 12, 2026