Pumilio paralogs, PUM1 and PUM2, are sequence-specific RNA-binding proteins that are essential for vertebrate development and neurological functions. PUM1&2 function to negatively regulate gene expres

NIAID Data Ecosystem20

The fission yeast MTREC complex targets CUTs and unspliced mRNAs to the nuclear exosome [RNA-Seq]. Schizosaccharomyces pombe

RNA降解机制

转录后质量控制

Cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome, however, the way they are recognized and targeted to the exosome is not fully understood. The recently identified Schiz

NIAID Data Ecosystem20

Fig4B_RACE_STOML2_R1_AI8.sgd

RNA降解机制

流感病毒PA-X功能

HEK293T ishXrn1 cells were treated with doxycycline for 3-4 days to induce knock down of Xrn1, then transfected with PA-X from the influenza A/Puerto Rico/8/1984 (H1N1) or vector, and luciferase repor

Figshare2023-01-19 更新30

ExtData_Figure_5_replicates

RNA降解机制

病毒-宿主相互作用

(A) HEK293T ishXrn1cells were treated with doxycycline for 3-4 days to induce knock down of Xrn1, then transfected with luciferase reporters containing insertions of the indicated lengths from the BCA

Figshare2023-05-01 更新20

small fragments in xrn1dom34. Saccharomyces cerevisiae

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