Single Cell Sequencing Analysis for Wolfram Syndrome (WS4) Unedited and Corrected Stem Cell-Derived Beta Cells
收藏NIAID Data Ecosystem2026-03-12 收录
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We revealed transcriptome differences between corrected and unedited (diseased) Wolfram Syndrome patient stem cell-derived beta cells. We also identified several endocrine, pancreatic, and non-pancreatic cell types in the samples populations. Single cell RNA sequencing of human Wolfram Syndrome patient stem cell-derived beta cells and other stage 6 cells derived from differentiation protocol. The cells were differentiated from both diseased (unedited) and CRISRP/Cas9-corrected induced pluripotent stem cells.
创建时间：
2020-09-21
