Critical Analysis of Prescriptions Medicines for Problematic Crack Use

Abstract A descriptive, exploratory and retrospective study that analyzed medical records of the patients under treatment for crack use; prescriptions and medicines interactions were collected, and the sociodemographic profile of these patients. Revisions of narrative literatures were conducted to verify which medicines have the greatest therapeutic potentials and to characterize the profile of the crack users; data from the medical records and the literature were triangulated. The results suggest: medicines prescribed in the treatment of the crack use are limited, medicines used in practice don’t have evidence of efficacy, there are relevant interactions in the prescriptions, and the sociodemographic profile of these users is similar with the literature. Additional studies are desirable to seek effective medicine treatment for crack use.摘要 本研究为描述性、探索性回顾研究，针对接受快克（crack）成瘾治疗的患者医疗记录展开分析，收集了患者的处方信息、药物相互作用数据以及社会人口学特征。研究开展了叙事性文献综述，以明确具备最佳治疗潜力的药物类型，并刻画快克成瘾使用者的人群特征；同时对医疗记录与文献数据进行三角验证。研究结果表明：用于快克成瘾治疗的药物种类有限，临床实际使用的药物暂无有效性循证支持，处方中存在具有临床意义的药物相互作用，且该类使用者的社会人口学特征与现有文献报道一致。未来亟需开展更多相关研究，以探索针对快克成瘾的有效药物治疗方案。